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Friday, October 13, 2017 4:47:46 PM
Dr. Missling has been quiet about the second P2a, the 104 week trial that is supposed to track long term safety.
Of course there has been reasonable speculation that what this is really doing is confirming the first P2a, with the doses optimized.
If the results are the same or better, it confirms the victory, and makes the P3 the war you go to already knowing you have won.
At the very least it provides more data to ensure the P3 is a winner.
Now...my thesis is most of Wall Street only wakes up and takes notice when there is an Approval by the FDA, or at least the definitive P3 results are released. If positive we could see AVXL rise 600-700% in a day.
So...it makes perfect sense to stay mum about the second P2a data...if you publicize it, the market still wont fully recognize it. But a sophisticated BP would understand, and AVXL would be in danger of being bought out on the cheap.
The final answer must be so clear and unambiguous that the market will be compelled to give us a proper valuation. Only a large P3 or FDA approval can provide that.
And Dr Missling has stated publicly that P2 is to determine if a drug works,you spend the big money on P3 when you already know it works and just need confirmation.
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