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Re: tradeherpete post# 124044

Wednesday, 10/11/2017 5:46:43 PM

Wednesday, October 11, 2017 5:46:43 PM

Post# of 473311
trade...agree but would emphasize that DR M has said (evidence indicates) A2-73 will restore CNS cellular Homeostasis (see falconer for details). We are in the process of validating that claim (some would say AGAIN). There is a distinction between validation of a process and claiming a compound will produce results X or Y, cure, etc. In the classical quality sense validation is the reproduction/repeated method to prove that a critical outcome which cannot be measured/verified like welding w/o destroying it(in this case AD by autopsy) will consistently produce conforming/complying products. "So what you say"? Well, this A2-73 becomes a piece of cake from a trials standpoint. We claim A2-73 treatment will result in a CNS cellular change (see falconer), this process of change will mitigate AD symptoms(among others). So, instead of trying to hit a bullet w/a bullet he is changing the game completely. There will be no debate, the process either works or it does not(see Falconer). IMO, this different thinking is the basis for his "tip of the iceberg" comment. More to follow.

A subtle but critical change from the old school thinking of hiting a bullet w/a bullet.

And the last 10 years of looking for some relief from Alzheimer’s has born out the theory that the chances are very remote anyone is going to come up with a drug that works

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