Amarin Corp Plc (AMRN)

[HDGabor]

r-

what you and I know matters not - what matters is how the prescribing physician and Insurance companies - think

Mostly agree, as it looks like you belongs to the average prescribing physician ... as a family Doc trig lowering meds is one of 2000 other meds for you.

Docs are thinking ... well if Vascepa is going to reduce CAD by reducing trigs - Lovaza will work even better ... so they are reaching for the Lovaza

[You] are thinking ... well if Vascepa is going to reduce CAD by reducing trigs - Lovaza will work even better ...

TG ≥ 500 and ≤2,000 mg/dL

- Lovaza
a.) -51.60% vs placebo, -44.90% vs baseline ... baseline TG 788 in placebo and 816 in 4g group ... EOT (calculated) TG 450 in 4g
b.) -14.00% vs placebo, -26.80% vs baseline ... baseline TG 624 in placebo and 655 in 4g group ... EOT (calculated) TG 479 in 4g
- Vascepa
a.) -33.1% [-46.6, -21.5] vs placebo, -26.6% [-41.1, 0.0] vs baseline ... baseline TG 703 in placebo and 680 in 4g group ... EOT (calculated) TG 499 in 4g

Lovaza isn't really better (slightly only) for TG ≥ 500 and ≤2,000 mg/dL ...

TG 200 to 499 mg/dL

- Lovaza: -23.20% vs placebo, -29.50% vs baseline ... baseline TG 271 in placebo and 268 in 4g group ... EOT TG 260 in placebo and 182 in 4g group
- Vascepa: -21.50% [-27%, -16%] vs placebo, -17.50% vs baseline ... baseline TG 259 in placebo and 265 in 4g group ... EOT TG 270 in placebo and 221 in 4g

Lovaza is better (by 12% vs baseline and by 1.70% vs placebo), but it does not overweight the AEs in this population

It is so funny that you have a logical argument (and I agree with your view) "why don't doctors know that Lovaza raises LDL?", but forget it, ignore yourself in case of "LOvaza numbers are better than Vascepas"

At this point I think I need to open a consulting firm for pharmaceutical marketing. AMRN has received advice from me worth significant $. I raised the OTC issue several years ago - the insurance issue - and their failure in design study to name a few

Thanks, it is better than any drug to manage mood (if necessary) ... LMAO

Best,
G