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Re: raja48185 post# 120976

Wednesday, 09/20/2017 5:38:24 PM

Wednesday, September 20, 2017 5:38:24 PM

Post# of 459921
raja..

Finally, going by what he has said before, the company plans to start 3 trials during the 2H of this year. We only have 100 days left and I am sure starting 2 out of 3 in the next 100 days would not damage his credibility, as long as he comes out at the right time and gives an update with a solid plan or reason for delaying the 3rd trial (I still think, he can pull it off - technically at least by announcing in mid December that they are open for enrollment for the 3rd trial - assuming that it is AD trial).

This brings an interesting question - does he have enough data from the extended trial for him to finally decide that he would go for the Rett trial, followed by AD trial and push the starting of PD trial to the 3rd slot? Is that the reason for trying to sell some shares to LPC - to ensure full funding for the AD trial? These are just my thoughts - trying to figure out the reason why Missling is quiet, the delay, total lack of communication/rumor. Of course there is a possibility that the extended trial data is not as good as expected - wont be a big surprise.




My concerns about silence are based on conventional retail (Rah..Rah) Ceo style being completely absent, more than that, we have a vacuum. This really challenges my belief thing. But on the other hand he has been consistent since the last phony legal action crap by giving no opportunities for parasites away. The bad news is we get silence, which is simply not sustainable.

I think he does have sufficient data to drive deals and that he has been doing exactly that. His master protocol is around CNS Homeostasis and the restorative/regenerative properties of A2-73. This is all about validation/proof of that thesis. Recent pubs on FDA adaptive protocols provide exactly the opportunity of the century to AVXL. If AVXL can prove that restoration of CNS Homeostasis enables all the recovery that Falcon describes and that each indication then has it's own efficacy profile, which all makes sense. It is hard to believe that all these what if links exist in real life, but they do in fact exist right now. At least two trials (RETT-PD) can be run simultaneously and concurrent with AD, based on funds/sponsors now available, IMO. I also believe the FDA has a big stake in this work by supporting new trial rules. My belief is the A2-73 trials are part of the roll out plans and I am praying for a massive success. I acknowledge my read is not supported by any known pubs but like no contradictions exist to the Homeostasis thesis at this point, neither do any exist for my version of what is about to happen. It is all possible.

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