Anavex Life Sciences Corp (AVXL)

[Talon38]

Fireman. More than likely it's a combination the size of the P2 with most of the patients being in the Melbourne area versus spread all over OZ. Then the 25 remaining are in a stabilized regime rather than the impressive and stark reversal status witnessed early in the trial. The Australian managers of the P2 have indicated that they are awaiting guidance on the P2/3 phase. And that awaits FDA/CDER final decision on what the AVAVEX 2-73 P2/3 will be. Using Gottlieb and Woodkock's 21stCCA modeling architecture will drive the recruiting of participants and that will have to be coordinated thru AUSG Medical/Health Agencies as well as Alfred Health as the sponsor of the trial in Australia. If there is another arm of the trial here in the US or elsewhere, that adds to the complexity. As to Aussie media, their attention span is no greater than ours...on to wars, fires and politics. Still it would be great to see "Ern Heaven Part II".

As we should all understand, there are a lot of moving parts to Alzheimer's drug development and much of it CM and ANAVEX have little control of. The ball is on the FDA side of the net and we are waiting for their return. Our time will be better spent tracking the progress of the Rett Syndrome trial.

Did you get down to fight any of the fires here in Oregon? We have be in the thick smoke in Southern Oregon for 6 weeks. The largest fire, the Chetco-Bar fire, is approaching 200,000 acres and is only 5% contained. It will take winter rain and snow to put it out!

Stay safe. Talon