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Re: alphapuppy post# 132208

Thursday, 08/31/2017 9:10:18 PM

Thursday, August 31, 2017 9:10:18 PM

Post# of 732157
Alpha puppy - thank you for your work on this.

One thing I noticed when I was reading your initial post is that you indicated that you added 83 days to IMUC results because they began their count at admin of treatment. It seems you think DCVax’s start day is at surgery. But it is not.

DCVax-L trial calculates both PFS and OS at randomization - 3 months in, which sounds similar to IMUC’s trial's number of 83 days.

So DCVax numbers DO NOT begin at surgery.

In order to compare the IMUC Trial to the current DCVax-L trial control patients, however, one must add 83 days to the IMUC results because the IMUC data time 0 for PFS was upon first administration of immunotherapy (ie after surgery and RT) whereas the DCVax-L Trial (and every other major trial in this disease) calculated the start day 0 for the PFS curves at the date of surgery.



I’m not sure if I’m misreading your post, but if that is what you think, I would love to see your chart with that new information in mind.
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