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Re: Evaluate post# 131985

Wednesday, 08/30/2017 12:05:40 PM

Wednesday, August 30, 2017 12:05:40 PM

Post# of 704450
In addition to that key word "minimum", I think we are too quick to use "2" to predict the future. While the Dr. uses "currently" when referring to the rate, we don't know if 2 is an approximation over 24 months or 3 months, and how many of those months include no events.

"approx 2 OS events per month"

"it turns out that the death rate at this time is lower than anticipated"

So he anticipates the threshold to be reached, and that is based on past performance and not on knowledge that 2 subjects are about to event.

That said, I don't doubt OS threshold has been more than reached. As a secondary endpoint it may not warrant a PR.
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