Anavex Life Sciences Corp (AVXL)

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Autism Hints, Yes

Might any of the Anavex sigma-1 receptor agonists provide useful therapies for any of the autism spectrum conditions?

There is no way to presently know with any certainty. But there are indications that Anavex molecules may be able to facilitate or promote favorable and normalized nerve connections.

I don’t know if there are murine (rodent) genetic and phenotype analogues of human autism. If there are, I’m certain Anavex scientists have or will be dosing those animals to assess any possible applicability.

This question touches upon the bigger, closely related question: Just what diseases and conditions might Anavex sigma-1 receptor agonists actually treat? Presently, only three are targeted: Alzheimer’s, Parkinson’s, and Rett syndrome. But the pipeline page of the Anavex website shows additional diseases and conditions being considered, for which there are apparently existing lab data. These are shown here:
http://www.anavex.com/pipeline/

But elsewhere heart disease, psychiatric conditions, and others have also been mentioned.

The spectrum of human (and animal) diseases and conditions Anavex Life Science Corp may eventually treat is broad, indeed. The unique and effective mechanisms of action of Anavex drugs, in restoring healthful cellular and organ system homeostasis, are highly suggestive.