Amarin Corp Plc (AMRN)

[ralphey]

Todays case



64 yo male prexisitng hx of dm2, hyperlipidemia and sleep apnea

Non compliant diabetic hgbaic at 10.4 – refuses injectables

Vascepa initiated 4/14 trigs 442

5/14 trigs 271

trigs 8/17 449

taking meds as prescribed

again isolated case - trigs have increased back to original levels as if med has become ineffective (odd it mimics last one ??) – could it just be worsening of diabetes which is out of control ? Certainly – yet other trig lowering meds dont seem to lose their capability in the face of escalating loss of glucose control ?


What does this mean ?

I dont know - its an observation of an existing reality in my daily practice ....

How does it make me feel ?

It give me an uneasiness about vascepa – because as stated - with other trig lowering meds I dont see this loss of control.

What did I do ?

This is a bit of a quandary as a diabetic hes on a statin - FDA says no to statin and fibrates (ineffective) using gemfiobrozil with statins – risks of side effects

My guidance?

Concentrate on controlling diabetes – stop vascepa, increase statin concentrate on diet and recheck lipids in 8 weeks