Anavex Life Sciences Corp (AVXL)

[A_Good_Day_2]

Don't take the following to sound harsh or cold. I want very much to see the end of this disease. I can't even imagine one of my daughters in this condition. Very sad. But here's how the business side of it looks to me:

From what I could find Rett Syndrome affects 1 in 10,000 to 22,000 females in the U.S.

If you take the average of this estimate you get 1 in 16,000 females in the US. US population is about 323 million. So we get about 10,000 female Rett sufferers in the US. We can estimate 75% of patients being prescribed (conservative IMO).

If we figure a monthly profit of say $200/patient (this is very conservative as well I'd say) we get monthly profits of $1.5M and yearly profits of about $18M.

These are just numbers based on the US. Actual worldwide profits would be much more.

Here's another thought...

Boys usually do not make it to term with Rett. They are either stillborn or die within days of birth. The genetic flaw is deadly to males.

What if genetic screening could be done pre-natal to identify the problem? Is it reasonable to think that maybe 2-73 could be administered pre-natal and could possibly preserve the male Rett babies??