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Re: Doktornolittle post# 128608

Sunday, 08/06/2017 7:56:03 PM

Sunday, August 06, 2017 7:56:03 PM

Post# of 708090
"That PR never even mentions mesenchymal. " (Not a Dupe Message)
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Your right. It only mentions methylation. I misread it somehow.

However, it worried me some when I thought it had mentioned mesenchymal. It worried me in light of the info Doc Logic just posted. If the MRI scan analysis means of detecting Mesenchymal is a recent improvement, as Doc Logic stated, and if biopsies are bad news because lack of homogeneity would force too much tumor removal, as Doc Logic stated... then things do not add up for mesenchymal detection in 2014.

But you are right. The 2014 PR does not mention mesenchymal. So this new MRI analysis could be something to argue with the regulators about. They would have to take into account your concern about the stats, but I don't believe that is necessarily a killer for that subgroup.

And if I were McCain, for instance. And I find my tumor measured to be mesenchymal via the new LL/UCLA MRI detection method, and NWBO presents stats that show, albeit a-posteriori (if that is a word) that this means DCVax-L has a good chance of giving you 5+ extra years, then I would probably insist on it. Then I would PR it all over the planet!
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