Monday, July 31, 2017 2:18:58 AM
I've already explained why it could theoreticaly be a consideration.
I never suggested smoking/edibles were superior.
What study did you reference? No matter, I mentioned IV only because I said transmucosal and transdermal are the most effective methods of delivery, other than IV which would have a 100% bioavailability.
CB1 receptors develop a tolerance to THC fairly quickly, which could affect IOP reduction. It's simply a concern, this is why it's important to account for risk when valuing a drug. We've discussed this - you (I'm paraphrasing) suggested Elsohly et al will figure it out, I thought that was strange and then went to Europe for a few weeks.
I simply asked vinpat whether or not he performed a valuation. If he did I'd be interested in knowing which valuation method and variables he used.
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