Wednesday, July 26, 2017 9:18:24 AM
I was unaware of the category.
And I am certainly unqualified to even guess at any potential
positive or negative effect of combining DCVAX with this category
of drugs.
With that out of the way .....
WOW - THANKS for finding this class of drugs .....
OVERVIEW
Use of Epigenetic Drugs in Disease: An Overview
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HEDD: the human epigenetic drug database
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The future of epigenetic drugs
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TRIALS - 2012
Trials with ‘epigenetic’ drugs: An update
www.sciencedirect.com/science/article/pii/S1574789112000968
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GBM
The good, the bad and the ugly: Epigenetic mechanisms in glioblastoma
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Advances in epigenetic glioblastoma therapy
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SURVIVAL
Epigenetics Drug Improves Survival in the Second Deadliest Cancer
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REPOSITIONING FDA-APPROVED DRUGS IN COMBINATION WITH EPIGENETIC DRUGS TO REPROGRAM COLON CANCER EPIGENOME
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GBM Trial - 1 example
Vorinostat and Bortezomib in Treating Patients With Progressive, Recurrent Glioblastoma Multiforme
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Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia
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BAD EFFECT
Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.
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