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Re: cabel post# 190705

Tuesday, 07/18/2017 8:21:22 AM

Tuesday, July 18, 2017 8:21:22 AM

Post# of 403747
much of what you write has no bearing on my point, but if others want to call it a smack down, then it is so, certainly, in the sense of a championship wrestling smack down.

Dose response means what it says. Is it that hard of a concept? IPIX has given up on small doses-50 and 100mg they did not show benefit. They showed some signs of efficacy, as modest as would allow them to continue on with p2b once again, for the record, ITT 7 of 29 vs 4 of 30 placebo, if I recall. That is to say a patient or two here of difference only. there is barely a response at 200 mg if at all. No real response at other doses. So, no dose response.

The other stuff is all well and good, the litany of points, but that was not my concern