Anavex Life Sciences Corp (AVXL)

[Steady_T]

My take is that the equity authorization was in fact part of grand bargaining stratagem in this sense.

As was pointed out there may not have been a partner offering terms that were acceptable to the company, there may have been none at all. We don't know. In either case the company needed the ability to go it alone for the immediate future.

It's not a bluff if you can do it. In this case I'd call it a backup plan or perhaps Plan B.

The Rett trial, if successful can be a big deal. The exact impact will depend on what the endpoints chosen for the trial are. If the endpoint is only reduce tremor and improved muscle control, that will be a positive indication for the PD trial but won't necessarily be a strong indicator for AD. If the endpoints are more comprehensive and they are met then the impact will be more significant.

If the Rett trial leads to an FDA approval, even with a very narrow label indication, that will ease the way for future trials and label extensions.

Everyone seems to assume that the Rett trail will be successful. It might not be. We shall see. Either way it is the endpoints chosen that will make the difference.