Sunday, July 16, 2017 6:35:34 PM
Why is it so hard to decide? For example, I looked at a competitor with a sample group of three. Well. they started with four. The fourth was ostensibly starting to show signs of improvement right before they died.
Another patient was reported to sit up suddenly like Lazarus and try to vocalize. The spin was that this was an improvement. Well, the compound had been previously shown to produce severe abdominal pains (in mice), so it seems more likely the behavior was due to that and an attempt to scream in pain.
Supposedly, another patient was now "playing pool". Well, how was their game? Were they actually playing before? Or , well, it's pretty easy to prop somebody up with a pool cue in hand and knock a few balls around.
It wasn't necessary to go much further. I not only felt leery, downright quesy at the spin factor at work here. Forget buying into that. though it meant "reading between the lines" a bit. Right?
Now we have, what, 25 or 30 sample group so far with Anavex. Kind of small but enough to get a decent indication. Reading between the lines, very positive indications. many very unambigious clinically tested and clinically credible reports of effectiveness.
A few dropouts. OK. Anything serious? No. These people are old, pushing 80, probably not all with a patient or sunny personality to begin with, one has to expect some to decide to quit. It may be a mistake but it's theirs to make.
I could well imagine some geezer saying" I'm tired of all this silly testing. I feel better. I'm going home!"
One of the reasons I rarely drink anymore compared to when I was young is that I no longer care for the accompanying dizziness and headache. So, same thing. Was the treatment making them deathly ill? No.
The only one that was what, level 2 had dementia. A neighbor's mother had dementia. He had to leave her alone for a couple hours and returned to find that she had built a bonfire on the front lawn. Said she was cold. It was July. The point is that people with dementia don't always exhibit good judgement. Still, they're not guinea pigs (or lab-rats whatever). They can quit whenever they want for any reason. We do know for a fact that no one dropped out for serious adverse events which would have been mandatory to report.
I'm simply sharing some insights on the decision process.
Speaking of graphics, perhaps you'll find the following as useful in that regard as I have. :)
https://investorshub.advfn.com/uimage/uploads/2017/7/16/dufakstock_decision.JPG
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