Skye Bioscience Inc (SKYE)

[AntonChigurh]

Old NMUS investor presentations

At the top of the page there is a link to a presentation by the former CEO on some Cannabis podcast thingy from mid 2015. Looking through youtube, I found two older ones and I pulled out a few things:

(jan 2015)

Regarding the Lock Guard RTO, Hollister had this to say about the Lock Guard guys who kept shares in NMUS 'I've met almost all of them personally' and 'there are HUGE supporters of what we are doing'

That last comment did not age well.

Interestingly, Hollister claimed at this time they were agnostic towards synthetic or natural cannabinoids, saying the approval process and economics would determine the direction they go. This is obviously much different two years later, with Murphy taking a strict 'we don't touch the plant' tagline.

Like Vinpat had said, Hollister claimed NMUS was a 'US based GWPH' and the company was initially valued as such. Unfortunately for those who bought at those valuations, the market didn't agree and they got creamed. I'm glad I don't hear anyone from the company claiming this anymore; important to DO YOUR OWN THING in life.

At this point, they only had licensed the one patent (THC-VHS) but said the patent was broad and had 66 'sub-claims' for different uses. Also referenced a THC patch that was licensed from the U of Texas that I haven't heard anything about.

(Mar 2015)

Hollister talks about Ingram joining the board 'great to have him because I don't have Any experience in Ophthalmology'...I couldn't believe he said something like that. Your a Boss of a pre-clinical biotech with a lead candidate in glaucoma and You Know Nothing about Ophthalmology. Yikes.

He also discusses that the sector has been against cannabis because while it may lower IOP, it also lowers blood pressure throughout the body, counteracting the positive effects. NB1111 delivery system takes care of this.

In both of these, they list MS and epilepsy as research candidates. Was their original plan to go after GW's indications, before realising this was not smart?

In general, I continue to Be super unimpressed Hollister. He was getting paid six figures to go on these webcasts and respond to questions from the audience that could be answered with a 5 minute google search:

'How much money will you need?'
'Why did you choose a rabbit model and will the effects be similar in humans?'
'Whats the difference between a bio tech and life sciences company?'

and Everytime he responds 'GREAT QUESTION THANK YOU SO MUCH FOR ASKING...'

Anyway, it is good to see that while the path has been a windy one, the thesis hasn't changed = glaucoma lead candidate, take advantage of UM IP, target designations with unmet medical needs that have research supporting cannabinoid efficacy.

Vinpat, when did CINV start to become something they were pursuing?

GLTFA DYODD