A new explanation.
The rather remarkable cognition, soporific (sleep-inducing), and other positive outcomes documented in the Australian Phase1/Phase2 trial have been imputed by some to be elements only of the placebo effect, not authentic drug-induced symptomatic relief.
It is projected that the ensuing full-scale double-blind Phase3 clinical trial will demonstrate that Anavex 2-73's favorable outcomes were merely poorly-controlled or poorly-assessed placebo effects; that the drug offers no authentic or persisting efficacy against Alzheimer’s symptoms. Hence, its approval by the FDA and purchase or ownership in AVXL equities is unwise.
With a profound need for subsequent substantiating in vivo (in the living brain) neurological studies, I’ll then propose this:
Anavex 2-73 has, except for a few, fooled everyone. It’s Central Nervous System treatment efficacies, as determined in transgenic rats, and putatively detected in several dozen Australians, are all just placebo effects.
This is rather stunning, and needs investigation. In fact, just how a rat can perceive or believe it’s being artificially treated with an unknown control substance, while the rats in the cages in the next room, with identical genetically-manipulated (trans-genic) diseases, are being treated with some “real drug” needs investigation. Here’s the answer. I encourage laboratory authentification of this, please.
In fact, Anavex 2-73, may or may not be a restorer of neuron homeostasis and Central Nervous System health (depending, perhaps, on ones perception of the future values of AVXL shares).
In fact, it would then appear that Anavex 2-73 is a new molecule of a new class of high-efficacy drugs. It’s the first drug of hyper-placebo-osis, where it induces such a profound placebo effect on parts of the brain that control emotion and cognitive perception that it causes those brain regions to biochemically suppress toxic chemicals (such as the beta-amyloids and tau tangles of Alzheimer’s), and send previously unknown or undetected nerve signals to all neurons in the body, causing them to re-constitute youthful, healthful homeostasis.
Hyper-placebo-osis is the phenomenon; found only in Anavex 2-73, and perhaps later in its analogues (Anavex 3-71, et al.). All new brain science. Inasmuch as no other mechanism of homeostasis restoration by Anavex 2-73 can be explained by those certain of the placebo explanation, hyper-placebo-osis must be the explanation.
You heard it here first. Anavex 2-73-induced hyper-placebo-osis.
