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stealthways

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stealthways

Re: None

Thursday, 04/06/2017 5:03:57 PM

Thursday, April 06, 2017 5:03:57 PM

Post# of 462470
P300 is pure data ...it omits a lot of ambiguity in more subjective data or data that involves more human "handling" ..... as a result you do not need as big a data set to have meaning, as with other metrics... I would think a very small n (maybe even "tiny") would be significant if data is correlated ....
I would love to know how the P300 is showing in the PK/PD ...for example are positive p300 results dose dependent (that would be huge imo); are P300 results sharply coorelated to certain strong responders etc.... P300 , if responding, would seem to be an IDEAL fit in an adaptive trial also.... almost like keeping patients constantly connected and monitored with dose changes (even when they sleeping as an example)... talk about gathering data....
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