Bill Gates, Steve Jobs, and Mark Zuckerberg dropped out of college. Maybe MYDX CEO is over educated.
Daniel Yazbeck
Market Expertise
Drug Discovery and Development Market
Cell Biology Market (Biochemical and Cellular Assays)
High Throughput Screening Market
Genomics Market (Sequencing | Microarrays | Diagnostics)
Proteomics Market
Laboratory Supplies Market
Medical Diagnostics Market
Point of Care Diagnostics Market
Molecular Diagnostics Market
Technical Expertise
Pharmeceutical and Medical Industry
Good Manufacturing Procedures (GMP)
Standard Operating Procedures (SOP’s)
FDA regulations
CFR Part 11 Compliance
Organic Synthesis
Biocatalysis and Biotransformations
Microbiology
DNA / RNA Synthesis
Sequencing
Protein Microarray and DNA Microarray Screening
Electrophysiology
Molecular Assays Development
Chromatography
Spectrophotometry
Electrophoresis
Radiolabelling
Molecular Biology (Cloning, Gene Expression)
Analytical Instrumentation (LC-MS, NMR, GC, CE, HPLC, robotic handlers, UV-platereaders)
Semiconductor and Consumer Electronics Industry
MEMS/Precision Etching Technology
Ferroelectric Thin Film Deposition Technology
Acousto-Optic Technology
Ultrasonic Separation Technology
Wireless Technology
Substrate and Mounting Technology
Publications
(Main Contributor is First Author)
Daniel Yazbeck; Martinez, C.A. ; Hu, S.; Tao, J. Challenges in the Development of an Efficient Enzymatic Process in the Pharmaceutical Industry. Tetrahedron Asymmetry, 2004, 15, 2757-2763.
Daniel Yazbeck; Tao, J.; Martinez, C. A.; Kline, B. J.; Hu, S. Automated Enzyme Screening Methods for the Preparation of Enantiopure Pharmaceutical Intermediates. Adv. Synth. Catal . 2003 , 345 , 524-532.
Daniel Yazbeck ; Durao, P. J.; Xie, Z.; Tao, J. A High Throughput Metal Ion Based Methods for Nitrilase Screening, J. Mol. Cat. B , 2006, 39, 156-159 (special issue).
Daniel Yazbeck ; Derrick, A.; Panesar, M.; Deese, A.; Gujral, A.; Tao, J. Enzymatic Hydrolysis of Racemic and Cis/Trans Ethyl Bicyclo[3.2.0]hept-6-ylidene-acetate: Solvent Effect and NMR Study, Org. Process. Res. Dev. , 2006 , 10 (3), 655 -660.
Rossi, F., Daniel Yazbeck, et. al. Process Research and Development and Scale-up of a 4,4-Difluoro-3,3-dimethylproline Derivative. Org. Process. Res. Dev., 2008, 12, 322–338
Xie, J.; Feng, J.; Garcia, E.; Bernett, M.; Daniel Yazbeck ; Tao, J. Cloning and Optimization of a Nitrilase for the Synthesis of (3S)-3-Cyano-5-methyl Hexanoic Acid, J. Mol. Cat. B, 2006.
Hu, S.; Martinez , C.; Kline,B.; Daniel Yazbeck ; Tao, J. Efficient and Scalable Enzymatic Process for the Production of (2S)-4,4-Difluoro-3,3-dimethyl-N-Boc-proline, a Key Intermediate in the Synthesis of HIV Protease Inhibitors, Org. Process. Res. Dev., 2006, ASAP 2006:239222 (special issue).
Lijian Chen, Young Mi Kim, David J. Kucera, Katheryn E. Harrison, Sogole Bahmanyar, Jill M. Scott, and Daniel Yazbeck. Fluorination-Free Synthesis of a 4,4-Difluoro-3,3-Dimethylproline Derivative. J. Org. Chem. 2006, 5 (3) .
Hu, S., Tat, D., Martinez , C., Daniel Yazbeck , Tao, J. An Efficient and Practical Chemoenzymatic Preparation of Optically Active Secondary Amines. Organic Letters, 2005 , 7 , 4329-4331.
Martinez , C.A. , Daniel Yazbeck , Tao, J. An Efficient Enzymatic Preparation of Rhinovirus Protease Inhibitor Intermediates. Tetrahedron. 2003 , 60 , 759-764.
Daniel Yazbeck , Damha M.J. Molecular Requirements for degradation of a modified sense RNA strand by Escherichia coli Ribonuclease H1. Nucleic Acid Research. 2002, 30, 3015-2025.
Daniel Yazbeck. Molecular Requirements for Degradation of RNA in DNA/RNA Hybrids by RNase H. MSc. Thesis, McGill University, Montreal, Canada, 2001.
Daniel Yazbeck; Derrick, A.M. Resolution of racemic cis/trans ( 1R,5R)-Ethyl bicyclo[3.2.0]hept-6-ylideneacetate using Candida Antartica Lipase B. Industrial Biotransformations, Wiley-VCH, 2nd edition, 2005.
Patents
(Authorship in Alphabetical Order)
Hu, S., Martinez, C., Tao, J., Yazbeck, Daniel. Methods for the Preparation of Stereoisomerically Enriched Amines. 2005 . WO 2005/054186 (world patent).
Hu, S., Martinez, C., Tao, J., Yazbeck, Daniel. Efficient Microbial Preparation of Capravirine Metabolites M4 and M5. 2005 . US 2005/0043361A1.
Matthews, C., Mitchell, M., Scott, R., Yazbeck, Daniel. Method For the Preparation of HCV Polymerase Inhibitors, 2004 , PC32421 PROV.
Derrick, A., Yazbeck, Daniel. Intermediates In The Preparation of Therapeutic Fused Bicyclic Amino Acids, 2003 , PC025386PGS (U.S. Application Serial No.: 10/677,83)
Chen, L, Borer, B., Kline, B., Lee, S. Michell, M., Martinez, C., Sakata, S., O’Neill-Slawecki, S., Tao, Junhua, Yazbeck, Daniel. Preparation of AG7404 Chiral Intermediates. 2003, PC25397.
Hu, Shanghui, Martinez , C., Tao, J., Tat, D., Yazbeck, Daniel. An Efficient Preparation of Enatiopure Secondary Amines by a Protease Catalyzed Kinetic Resolution. 2003, PC25652.
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