Amarin Corp Plc (AMRN)

[HDGabor]

JL-

Addition to "The first point is that EPA and DHA on the whole have some similarities, both lower trigs..DHA more so on a per dose basis."

- Lovaza "MARINE trial" had TG 816, meanwhile V had TG 680 at baseline ... Lovaza with TG 655 at baseline showed less / worse TG decrease (Figure 2)
- Lovaza vs V "ANCHOR" trial (TG 200-499)(Figure 3)
> TG: -23.2 vs -21.5
> TC: -3.1 vs -12.0
> LDL-C: +3.5 vs -6.2
> Non-HDL-C: -6.8 vs -13.6
> VLDL-C: -20.3 vs -24.4
> Apo-B: -2.3 vs -9.3
> HDL-C: +4.6 vs -4.5

Best,
G

ps: Figure 2 & 3 are from A Comparative Overview of Prescription Omega-3 Fatty Acid Products