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Re: gr8db8 post# 644

Friday, 02/24/2017 6:14:16 PM

Friday, February 24, 2017 6:14:16 PM

Post# of 2099
Right, and if they receive a single Avastin infusion and drop out, they are then included in the survival analysis. If they receive a single VB-111 infusion, they are included in the analysis. The trial had planned to enroll 252 and ended up enrolling 256 patients....so there can't have been too much of a responder overload. Obviously, those who remain in the trial after 5-6 months are by definition responders, but that is true in any trial of rGBM patients by definition considering the median overall survival.

The interesting post-hoc analysis might be comparing patients who received checkpoint inhibitors and VB-111 compared to those who did not.
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