Amarin Corp Plc (AMRN)

[Whalatane]

VU Interesting post. Have U looked at

theheart.org on Medscape
The Primary Endpoint Is Positive: What More Do You Need?
Gregg W. Stone, MD ...2017

Probably must reading for anyone seriously discussing R-IT

Consider your pts re previous trials . The world does not stand still
Look at the use of drug eluting stents , long term duel antiplatelet therapy ..low dose aspirin daily plus clopidogrel ...DAPT trial ...

In conclusion, among patients treated with drug-eluting stents, continuation of thienopyridine-plus-aspirin therapy, as compared with aspirin therapy alone, beyond 1 year reduced the risks of ischemic events.
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So in the R-IT population you now have more use of drug eluting stents and longer treatment with low dose aspirin and clopidogrel

My pt ..IMHO those in R-IT , at least in the US are benefitting from incremental improvements in risk reduction ...developed and implemented since R-IT was designed .


Therefore the placebo rate will be lower then what most on this board expect it to be .
JMO
Kiwi