Anavex Life Sciences Corp (AVXL)

[XenaLives]

From your article -

Although the MMSE is useful as a screening tool and as a marker of cognitive change in patient groups, to our knowledge, its utility as a measure of change in individual patients has not been determined. During follow-up of an individual patient, the standard required for a test to be a useful measure of progression is different than in the analysis of group data. Although score changes for patients can be reliable and meaningful when averaged over the entire group, the same magnitude of change may not be reliable or interpretable when observed in one patient measured on 2 occasions. This study examines the long-term variability of periodic MMSE assessments to determine the utility of the MMSE to follow progression and help guide the clinical management of individual patients with probable AD.

http://jamanetwork.com/journals/jamaneurology/fullarticle/775209

This is a 1999 analysis of older data. It is a discussion of using the MMSE to evaluate individuals and how unreliable it can be.

Anavex used multiple scoring methods, not just MMSE.

The article cites no comparable data to the lifestyle improvements seen in the piano player, the painter, the golfer, and the mass transit rider, and of course Mr. Haven.