NorthWest Biotherapeutics Inc (NWBO)

[Dan88]

Actually what he said is very bullish in my opinion. My interpretation of his words is that there is a growing ethic concern for the company to release the data (he believes that the data is there and have been kept for more than one and one half years) by the company if HR is anything close to 0.7. So by keeping it, it is unethical!

So he guessed since the company has not released the data because HR is no way close to 0.7, the trial might be have some problem; otherwise why the company has not published the data or why FDA has not stopped the trial due to an overwhelming success (indicated by 0.7 HR in August 2015).

When he was talking about that, he might be just appeasing his host (MD Anderson) who is strongly again nwbo, or maybe against anything not chemo, by even forgetting what he was talking about is called immunotherapeutic vaccine in which it is very rare one would see a success at such an early time of the trial, let alone a success with such an overwhelming efficacy evidence indicated by 0.7 HR.

So the worst of his guesswork regarding DCVax-L p3 trial data is that in August 2015, there must have had no obvious treatment efficacy (HR0.7) because if that is not the case, then the company would have released the data by now due to strong ethic concern.

Well, the HR was not 0.7 at that time (it is even not in my wildest imagination that I would think that could be the case), but it may just be close to 0.7 now or in the near future.

Then, if that is true, there will really be an ethic concern for the FDA to stop the trial before the 233rd OS event is reached so that the magic vaccine (at 0.7 HR) can be made available to suffering patients ASAP.