NorthWest Biotherapeutics Inc (NWBO)

[Dan88]

Not any of the experts you ask your question to but I will try. Docs in the video are just talking the obvious truth that they have not seen huge immune response with DCVax-L in their site for a dozen of patients treated.

Should they or us expect huge immune response from DCVax-L? If your answer is yes, then you certainly have not done your DD.

The very fundamentals of DCVax-L is 1) its pristine safety profile, which is a big plus; and 2) not yet approved efficacy.

You can check 1) now, and as long as the 2) is concerned, nobody knows at this time but the final results will be out, maybe as early as late March but not later than June.

If you believe Dr. Liau has said, "all patients live longer," then the only worry if any should be if there is indeed some separation. If yes, DCVax will be an approved treatment this year.

On the other hand, the fact these doc in this one site in treating a dozen of patients observing no huge response is actually a good thing besides it is an obvious truth, which any investor should be aware of because it means our worry about pseudoprogresssing "wreak havoc" may be just overblown in and of itself.

And this should also not be a surprise at all since the pseudoprogreesors should be excluded from the trial according to the trial rules/protocol. This actually means the site has done a super job to truly exclude any pseudopressors from the main trial.

No one should expect DCVax-L would kill patients due to uncontrollable immune response, just as the case associated with Cart-t like Juno, etc., and that's the beauty of DCVax-L.