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Re: flipper44 post# 101099

Wednesday, 02/08/2017 9:12:56 AM

Wednesday, February 08, 2017 9:12:56 AM

Post# of 703749
Methylated patients do better in general apparently because they respond better to TMZ (maybe also to radiation). So methylated mesenchymals doing better would not be a surprise. But according to LL, the mesenchymals are disproportionately unmethylated.

I am not suggesting that they remove TMZ from mesenchymals, but rather, from all unmethylated patients, which would apparently include the majority of the mesenchymals.

And they do have a good way to detect whether patients are methylated or not according to LL. A method that is now in common use. Not sure they used to have such a method back when the TMZ label was granted eons ago.
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