NorthWest Biotherapeutics Inc (NWBO)

[Doktornolittle]

Methylated patients do better in general apparently because they respond better to TMZ (maybe also to radiation). So methylated mesenchymals doing better would not be a surprise. But according to LL, the mesenchymals are disproportionately unmethylated.

I am not suggesting that they remove TMZ from mesenchymals, but rather, from all unmethylated patients, which would apparently include the majority of the mesenchymals.

And they do have a good way to detect whether patients are methylated or not according to LL. A method that is now in common use. Not sure they used to have such a method back when the TMZ label was granted eons ago.