Anavex Life Sciences Corp (AVXL)

[apostrophe]

re: "...long-term lowers mental function"

Obviously, one would be surprised if someone scored higher on an IQ test as a result of being in a constant state of inebriation spanning many years. We would expect their scores to go down. So moderation could be argued in any case. Various myths and belief systems aside, consider the following:

Cannibanoid receptor signalling is temporary and wears off after a while as the additional cannibinoid leaves the system and receptor sites resume mundane interaction with cannibanoids naturally produced in the body.Cannabinoids found naturally in the body are called endocannabinoids. ‘Endo’ stands for endogenous, meaning within the body. They are non-toxic.

( http://www.leafscience.com/endocannabinoid-system/works/cannabinoids/ )

Alcohol (for example, Bourbon) is proven to kill brain cells and proceeds to destroy your liver in the process of lowering your mental function. There are no alcohol receptors. Alcohol works by paralyzing the outer layer of brains cells where mental inhibitions reside, then the paralysis spreads inward as it soaks into the interior of the brain. If consumption continues, it finally reaches the autonomic area, resulting in death. A certain percentage of the paralyzed brain cells never recover each time. It is a poison.

There is nevertheless a strong cultural bias toward consuming alcohol to "feel good" though it is better suited as a fuel or industrial solvent.

I notice a similar bias to downplay toxicity in pharmaceuticals. Many of these huge clinical trials seem designed to try to find some evidence of efficacy no matter what. It's almost as if there is an unstated belief "how can it have any effect if it isn't toxic?"

Anavex 2-73 isn't toxic.