Aurinia Pharmaceuticals Inc (AUPH)

[puravida]

Barry- you may have already read this but I searched yesterday for other info on the 13 deaths and this is all I could find. I agree with you that the ph2 early data looks great but the 13 deaths are concerning me. I have yet to take a position here.

"Analysts at Leerink said that the stock was trading down because there were 13 deaths across the study, with 10 in the low dose arm of the drug. The company said however that these deaths were due to the severe underlying nature of the disease, and not its drug.

“While this does naturally raise questions, it is important to be mindful that these lupus nephritis patients were extremely sick and treated at many sites with differing practice patterns in Asia, some of which we believe were in much less developed places,” Leerink said in a note to clients.

“The company noted that there were no clear underlying patterns among the deaths, and that one patient (who achieved complete remission) for example had baseline proteinurea of 29 grams, which was the highest value they have ever seen in their entire career of treating lupus patients.”



Full article below:


http://www.fiercebiotech.com/biotech/aurinia-pharmaceuticals-lupus-candidate-aces-phii-prepares-for-fda-talks