Anavex Life Sciences Corp (AVXL)

[Rubyred77]

What is the thinking behind the pathogen hypothesis of Alzheimer’s?

Good read on this slow day.
http://www.news-medical.net/news/20170112/Could-pathogen-infection-really-lead-to-Alzheimere28099s.aspx

"So, in general the vast majority of the AD research field has focused and continues to focus on the pathology that occurs in the disease and not on the initiating triggers for this pathology."

"Also, clinical trials to obtain biomarkers based on infections as well as those for treatment using antivirals, antibacterials, and anti-inflammatory drugs are required to establish how treating for infection can potentially influence onset and/or progression of disease following early diagnosis."

"Is it likely that Alzheimer’s could be a treatable condition one day?
Yes, but we must identify the triggers of the disease first and focus on eradicating the triggering mechanisms, in this case infections, by using antibiotics, antivirals or other anti-infectives."

"Vaccines against amyloid and other naturally occurring entities in the body are probably not going to be useful in this disease and, to date, have failed in clinical trials."