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Re: MicroKing post# 86047

Thursday, 12/29/2016 8:30:42 PM

Thursday, December 29, 2016 8:30:42 PM

Post# of 463606
Molecularly Very Different

From the company's website:

vTv has identified novel non-electrophilic Nrf2/Bach1 modulators that can activate nuclear factor-E2 related factor (“Nrf2”) and inhibit Bach1 (the Antioxidant Response Element (“ARE”) transcriptional repressor) leading to potent activation of the Nrf2 pathway. The results from the laboratory of Dr. Thomas suggest (1) Bach1 may be a promising novel target for drug development against Parkinson's disease, and (2) vTv's compound, HPPE, may protect against nigrostriatal dopaminergic neurodegeneration by virtue of its ability to activate neuroprotective Nrf2/ARE genetic response in a preclinical mouse model of Parkinson's disease.

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Not at all related to or similar to Anavex molecules. It might well be a useful Parkinson's treatment. If so, well and good.

I'll stay with Anavex, however.
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