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blu_1

Re: Penny Double post# 84852

Monday, 12/19/2016 6:20:59 PM

Monday, December 19, 2016 6:20:59 PM

Post# of 465858
If Anavex were to patent and market Anavex Plus only, that would suck for those that are intolerant to donepezil, for which there are many. From a biochemical perspective, I would expect donepezil to hinder the effectiveness of 273 (hogs the sigma 1 receptors without doing anything there of benefit and proven to antagonize the activity of muscarinic agonists). Ph 2 results suggest that it does indeed do that
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