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Re: djmurdock post# 83154

Saturday, 12/10/2016 3:17:29 PM

Saturday, December 10, 2016 3:17:29 PM

Post# of 463611
"Any thoughts why AVXL isn't being more talked about?"

Yes. Anavex technology is utterly revolutionary. It is in no neurobiology textbook. It was never even remotely imagined by any of the world-class researchers in the room (except for the Anavex principals).

It rubs harshly against all of the pre-conceived Alzheimer’s pharmaceutical treatment options, of which there are only two: administer an acetylcholinesterase inhibitor (to, for only a period, facilitate otherwise diminishing thought processes), or, find a safe, effective drug that causes the removal of protein wastes (amyloid plaques, tau-protein tangles) in the neuron, either immunologically or by extraneous molecules.

None of these treatment approaches have shown any useful efficacy. Immunological approaches have had severe, debilitating side effects, and waste protein-clearing molecules, too, have all sorts of untoward outcomes (or simply don’t work at all).

Billions (yes, billions) of research dollars have been expended in these efforts — primarily by the researchers and corporate officials listening to the Anavex presentation at the conference. We can conjecture on the internal thoughts a number of the Anavex slides evoked: “Oh, feces, look at that! Symptomatic stabilization — even IMPROVEMENT. And no side effects, and orally administered. How am I gonna explain this to my Board of Directors? How am I now gonna get another million dollars for the new drug tests I want to work on?”

Don’t say a thing. Keep this all very quiet. Maybe it’l all just go away and everyone can go back to his lab and spend lots more on new immunology or waste-clearing drugs. “Otherwise, I got no future with my Big Pharma company. Say, where is that Anavex guy? Maybe he needs a new lab technician?”

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