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Re: neiu post# 81787

Friday, 12/02/2016 10:07:00 PM

Friday, December 02, 2016 10:07:00 PM

Post# of 459493
Yes, remember Galileo was imprisoned for holding the belief that the Earth revolves around the Sun. His belief went against all convential thinking during his time.

I suspect that today there is a bias and dependency of researchers's careers in pursuing and defending theories they have espoused. Billions have been spent on the amyloid palque theory. It's difficult to admit an error or failure to any degree. It may be that an amyloid plaque removal drug will eventually prove to be helpful after we address the root cause of Alzheimer's disease. However, up to now the amyloid plaque hypothesis has been a failure.

No drug to date has demonstrated any treatment to even slow the progression of Alzheimer's disease. The latest reports we have received about the AVXL 2-73 clinical trial suggest that patients in this small study have not experienced the expected ongoing cognitive decline normally expected in Alzheimer's patients. Indeed, the reports this summer and fall claim that AVXL 2-73 clinical trial patients show "improvements on tasks within the Cogstate battery''. This suggests that there is hope that AVXL 2-73 may prove to slow the progression of Alzheimer's disease in some patients. If so, that is a first as difficult as it will be for convential thinking to accept.
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