Anavex Life Sciences Corp (AVXL)

[XenaLives]

Notes on the interview, comments welcome, just what I heard :

1)Alzheimer's first indication company is focusing on.

2) It is Chronic and incurable, AVXL works upstream from the disease.

3) There is no effective treatment to halt or slow at this time

4) 2-73 is believed to address underlying cause and prevent progression

5) 2-73 works by restoring homeostasis of cells

6) Sigma 1 not utilized on a daily basis - is a safeguard.

7) 2-73 restores balance through s-1 receptor - Missling specifically states that there is a possibility to regain cognition

8) 2-73 said no difference in effect alone or with "other compound".

9) Retts and infantile spasms could go to market faster.

10) Missling had grandmother and grandfather with Alzheimer's.

11) Alzheimer's is a chronic disease, 2-73 is a maintenance drug, no safety issues for long term dosage expected caveat of 12 months which correlates with current experience timeline.

Note on personal experience - 12 mos of safety does not mean 24 or 36 months, I have experienced negative side of drugs that did not occur within a 12 month period. This is one reason why the extended P2 is so valuable to to company.

All in all very professional, conservative, but still encouraging.



Connection between AZ PK MS imbalance of homeostasis.

Compound is not the magic bullet, the S-1 receptor is

Last comment does put emphasis on delay of decline, but that does not negate the fact that he also said treatment could result in regaining congnition.