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blu_1

Re: TomP1 post# 78241

Tuesday, 10/18/2016 3:58:48 AM

Tuesday, October 18, 2016 3:58:48 AM

Post# of 463662
I just don't know if that bar can met for this trial design. If any patients are on 50mg/day 273 monotherapy, they have the best shot imo. Actually, the 7 on 273 monotherapy have been pretty stable through 31 weeks. I don't know what dosages they are on. Most donepezil trials show its mmse scores dropping after 3-6 months and sinking below baseline just after 6 months. 273 does have one important advantage over donepezil, it is much better tolerated.
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