NorthWest Biotherapeutics Inc (NWBO)

[longfellow95]

"What no one is telling you about BMS’ Opdivo immunotherapy trial failure"

http://medcitynews.com/2016/08/opdivo-immunotherapy-cancer-bms/?rf=1

It examines some of the 'hype' surrounding BP CI's:-

“What they’ve done is applied this very encouraging, very exciting, very novel therapeutic approach to a huge heterogeneous population of patients where only a small percentage really benefit, but there’s all this discussion about how this is a multibillion-dollar product for manufacturer XYZ,”Kolodziej said. “That’s hype, if you ask me.”

And:-

"Kolodziej characterized the lack of predictive biomarkers in drug development as a problem. The fault, he believes, lies largely with Big Pharma’s reluctance to spend time, effort and money in identifying which patients are most suited for immunotherapy drugs.

“My personal opinion is that the most important thing is getting to market,” he charged of drugmakers. “Nothing else matters. Coming up with a biomarker limits their market size – why would they do that?”

Worth a read.