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Monday, 08/01/2016 9:03:26 PM

Monday, August 01, 2016 9:03:26 PM

Post# of 459288
Mikesc is correct in his post to F1ash. The data is promising. Dr. Hooper wrote a good article published in Seeking Alpha today. A person, Maybull, made a negative comment about Dr. Hooper's article implying that the data from AVXL's clinical trial was not promising and that all Maybull wanted to know was whether it worked or not. A response to Maybull that I thought was good was as follows: "Maybull is simply argumentative. Maybull, you may be interested in knowing that no FDA approved AD drug is "working" so far. However, the clinical trial for AVXL 2-73 has established safety. Furthermore, the limited number of people in this trial show no significant cognitive decline and there have been unexpected therapeutic responses such as improved engagement with family and friends, improved mood, increased independent activity, feeling happier, improved alertness, better coordination, and better coping. All of this, no significant cognitive decline and the unexpected therapeutic responses, are at this point I believe better than any drug that has been approved by the FDA for the treatment of AD. That may not be understood by you to be "promising", but it is thought by patients in the trial to be promising. Patients have requested that the trial be extended so they may remain taking AVXL 2-73. Of course, the point of a P3 is to prove efficacy."
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