NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

Interesting. It could be both. Nature tends to conserve energy devoted to some functions while it enhances other. Take decreased reproductive capacity during times of drought and starvation in multicellular animals, and yet the ability to live longer can be enhanced during that very same time.

But I have wondered if they have less Immune Blockade function making them more immunogenic / vulnerable to DCVax-L, with some other survival features that normally offset this weakness, perhaps this horrifying fast travel mode being one of them. -- Dok

The epithelial to mesenchymal transition in forward likely reduces normal protective enhancements in favor of motility. I would not be surprised if blockade reduction was one of them.

I'd also not be surprised to find that the motility appendages themselves present a vulnerability, that is, if the cells are caught. Mobility in nature is typically a risk benefit calculation.

It's kind of like a mini-safari of prey and predator. Only, instead of cheetah and gazelle (and tortoises ), we are talking about about dendritic cells, cancer cells and mesenchymal epithelial transition.

This figurative analogy plays out again and again in nature. It does so in the oceans and on land. Why not on the microscopic level?

The amazing thing to me is that all this advanced micro-ecology can develop to such an advanced level in a host (human) that ultimately dies whether of the disease itself or simply old age. They do not pass cancer on -- in any communicable sense.