NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

Nice DD. If May truly was installation month for three different global hubs regarding DCVax-L, and NWBO doesn't believe the PSH actually caused more than about a 1 month delay, then I would assume they are not necessarily anticipating, or building into their forecasts a negative conclusion (aka:CRL).

I'm no expert on what these automated manufacturing "rows" will ultimately be composed of, but I have a feeling that when you've see one, you've seen them all, and any site installation will simply increase the number. Trained individuals to run and ensure quality control would be highly important. It seems Cognate needed to hire with public announcements for job positions while perhaps Germany and King'sCollege could prepare somewhat more internally?

If the "machines" were installed at all geographic locations, they'd almost certainly have end to end enclosure. All this scaling up would be followed by inspections which then might be followed by tests to demonstrate batch consistency, followed by further inspections that perhaps might be concluded with approval.

All timed to come out near trial's end. This would not be a strategy to "fail cheaply." Instead it would be a strategy to not only prepare for DCVax-L production for GBM, it would make it feasible to expand further (in Sawston?) for all solid tumor applications.