NorthWest Biotherapeutics Inc (NWBO)

[Doktornolittle]

"I am hesitant to get too involved."

I think that one safe piece of advise to any GBM patient is to seek out all possible genetic testing that might be useful to select a treatment, or trial, or compassionate use group with. It might be even more useful next week or next month. Just better to know.

I don't know how much testing is available and what the reimbursement is, but it is worth looking into. Look at all existing GBM trials and the relevant genetics, and you want to find at least the info needed to optimize you odds within each one.

Methylated or not is probably useful. That probably means the tumor, but they should find out if the broader patient genetics is enough of a clue, if the tumor is not available for such analysis.

Those 4 GBM groups are important. The Classical, Neural, Pro-Neural, and Mesenchymal.

And there are other trials targeting highly expressed (self?) antigens. Not sure why in the world they would work, but since they might work, should test for those. There should be a GBM panel available. Maybe not this minute, but maybe next week. Call Biden's Moonshot people and ask what a GBM panel would be. If there is no such thing yet, ask why not.