Avid Bioservices Inc (CDMO)

[mskatiescarletohara]

Jazz and BOT.....clarification.


I am talking about IDIX's and VRTX's ability to treat HCV and the potential that it can be administered to coinfected patients who are on HAART therapy. HCV SOC cannot be given to some coinfected patients due to the HAART regimen they are prescribed since not all HIV drugs can be given concurrently as there are harmful interactions from between the various anti-virals.

VRTX's and IDIX's compounds may interact well with some nukes prescribed in HAART therapy, therefore it can potentially carry an expanded label to treat coinfected patients.

I'm not sold on Bavi treating coinfected individuals as a monotherapy. I'd have to see some animal data to support such a conclusion, did SK mention they were conducting any preclinical work for this indication? The company is giving guidance they want Bavi in combo studies, there must be clinical reasons for this strategy.

katie....