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Wednesday, July 26, 2006 6:59:59 PM
I'm talking about one drug as therapy for both viruses.
Protease inhibitors can treat HCV and HIV. There are several PI's on the market for treating HIV. Both IDIX and VRTX's compounds are eligible candidates as is Bavi.
Do you begin to understand the unique issues involved with the future pricing of bavi?
Yes, as a matter of fact I do. One mab that can treat viruses and cancer should command different price structure depending on the indication, however, how does one differentiate pricing the mab for cancer, HIV, HCV etc.....I'll leave this up to BP's marketing expertise which PPHM clearly lacks.
The statement you reference can easily be misterpreted, I saw nothing in that statement referencing price structure.
My apologies to you, BOT, CJ and who ever else for my recent stern comments. I do appreciate your DD and commentary. I've been on vacation on and off the entire month of July, and frankly, am still highly pissed at some of the ridiculous questions and tirades on the recent CC. The complaints and screaming did more damage than good, I just pray the next CC will omit all private investor questions, shame, but true. With respect to the ongoing Phase Ib study, and one upcoming, I just don't even want to hear any speculation about....you know what. Lawitz is running this Phase Ib along with Godofsky and Lawitz is at bat for VRTX. I understand the importance of success of these two Phase Ib studies, sorry, but the speculative innuendo posted recently just set me on the defensive.
VRTX right now is clearly setting a path to get their drug approved on an accelerated approval basis for treating naive patients with results from their ongoing Phase II results. PPHM has a shot at treating non-responders, and yes, accelerated approval, too, if the patients in the Phase Ib mono repeat dose show 2 log or better drop. No dot connecting, this is real. It's absolutely imperative that these non-responder patients are screened properly, since it only leads to a broader protocol, Phase II. I would love to see BP come on board and finance two broad Phase II studies to treat non-responders only. I would also like to see Bavi and VRTX's drug in a combo study in the next year or two.
katie....
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