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JB3729

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JB3729

Re: Amatuer17 post# 64139

Tuesday, 05/31/2016 9:22:14 AM

Tuesday, May 31, 2016 9:22:14 AM

Post# of 469002
A standard trial gives each patient a particular dose.

An adaptive trial can give each patient any number of doses and looks for dose response and, I'm sure, PK/PD data at each individual dose.

We were told that AVXL's oral doses would be 30 and 50. Yet, somehow it was determined that 14 was the dose that stopped progression. Who knows what all they looked for and how many different doses were given to each patient.

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