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Re: circa1762 post# 64122

Monday, 05/30/2016 6:40:19 PM

Monday, May 30, 2016 6:40:19 PM

Post# of 462732
I'd like to see if 2-73 has more improvement in those with milder Alzheimers that is at an earlier stage than those that have more advanced disease.

The 5 week PK/PD data helps makeup for the fact that this is not placebo controlled Ph 2 trial. In a Ph 3 placebo controlled trial, we might see the placebo control group hanging with the 2-73 group improvement wise for the first 12 weeks, but then eventually the 2-73 group will pull ahead. But even at 12 weeks, I'd bet the 2-73 group will see more improvement than the control group.
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