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Re: circa1762 post# 63934

Thursday, 05/26/2016 5:24:20 PM

Thursday, May 26, 2016 5:24:20 PM

Post# of 458207
I agree, especially when reading things like Dr Fisher on 3-71:

"The effects of ANAVEX 3-71 appear specific since a pure M1 muscarinic agonist was less potent or not effective in the tested neuronal cultures, respectively.

It is believed that the effects of ANAVEX 3-71 are mediated by a concomitant activation of the M1 muscarinic receptor (M1R) and the S1R via an induced hypothetical heteromerization between M1R & S1R."
http://www.anavex.com/?news=anavex-presents-positive-results-for-both-anavex-2-73-and-anavex-3-71-in-alzheimers-models-at-2015-adpd-conference

I found the ultrasound article interesting too, also AU research. Seems a shame they can't take a non-invasive therapy like that straight to human trials.
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