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biopharm

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biopharm

Re: chenzo11 post# 263721

Tuesday, 05/10/2016 9:07:54 PM

Tuesday, May 10, 2016 9:07:54 PM

Post# of 345969
Many are realizing that PS exposure is a fact when the trouble begins...

Nov 29, 2013

A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3).

http://www.ncbi.nlm.nih.gov/pubmed/24121505

-----------------------

May 10, 2016

Phosphatidylserine exposure is required for ADAM17 sheddase function

http://www.nature.com/ncomms/2016/160510/ncomms11523/abs/ncomms11523.html#affil-auth

----------------------

2-Adam-12... 2-Adam-12... Code 6 still active

"Bavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that is the cornerstone of a broad clinical
pipeline." -- Big Pharmas nightmare... unless they are fortunate enough to have The Bavi Edge!

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