Anavex Life Sciences Corp (AVXL)

[bas2020]

Additional tidbit from the shareholders' mtg...

Dr. M did a great job of explaining the mechanism behind the science with regard to the Sigma-1 receptor, in that 2-73 has been proven to be an agonist (helper) to Sigma-1 which is an agonist to cell "health"...not just within the brain, but the entire body. Therefore, they believe that 2-73 might very well be proven, over time, to improve such things as heart health, as well. What an amazing new platform drug we're potentially witnessing.

Regarding potential early approval: It's very possible that 2-73 could be FDA approved for Rett's before Alz. If that happens, then 2-73 might be available sooner...and doctors could write prescriptions off label, for other indications.

Regarding AD P3 trial timing and potential FDA approval... It's been mentioned that the P3 trial will likely begin late this year or early next. Aricept was approved after 6 months into P3 trial.

So, between Rett's approval and Alz approval, you can draw your own conclusions with regard to early timing (potential).