NorthWest Biotherapeutics Inc (NWBO)

[Doc logic]

flipper44,

These are good asumptions. We should also compare these assumptions to the most neutral long argument from Rkmatters then,that PFS benefit is minimal but that OS could demonstrate significant benefit. Based on a most likely range of enrollment and event rates that led to the 66 events triggered in 12-2013 and comments by Dr. Prins and Dr. Liau that DCVax works in some subtypes better than in others, the treatment vs SOC PFS separation could be closer than originally expected from the Phase 1. We might also expect a strong separation in benefit from those who respond and those who do not based on the comments we heard.