NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

"[D]o you think NWBO screening halt has to do with the relatively new information on subtypes and now t cell levels? Maybe they want to take into account this information.

[1.] Would NWBO want to formally add to the trial design that they intend to consider these new filters before an interim analysis for efficacy?"

IMHO, it is a possibility, as it only affects the analysis.

"[2.] Would they also need or want to increase the trial size?"

IMHO, I don't think so, because it would be a major thing to change protocol that affects the ongoing trial proper at this point (like trial size). Besides, I think they likely already have plenty of patients to make determinations with the new immune response indicators.

What do you think?